Functional MRI Signal Fluctuations: A Preclinical Biomarker for Cognitive Impairment in Type 2 Diabetes?

Functional MRI Signal Fluctuations: A Preclinical Biomarker for Cognitive Impairment in Type 2 Diabetes?

Type 2 diabetes mellitus (T2DM) is associated with macrovascular and microvascular complications as well as an increased risk for cognitive impairment (CI), ranging from mild memory impairment to fully developed dementia (1). Both vascular dementia (VD) and Alzheimer disease (AD) dementia are increased in patients with T2DM. However, it is not clear if T2DM directly causes CI and dementia or if...

Relationship Between Caregiver Burden and Cognitive Impairment in Adult Patients with Type 2 Diabetes

Introduction: Caregivers play a critical role in health management of patients with chronic diseases. Caregiving is associated with experiencing different emotional and psychological problems. Objective: This study aims to determine the relationship between caregiver burden and cognitive function in adult patients with Type 2 Diabetes (T2D). Materials and Methods: In this cross-sectional stud...

Cognitive impairment and MRI correlates in the elderly patients with type 2 diabetes mellitus.

BACKGROUND exact mechanisms underlying cognitive dysfunction in diabetes mellitus (DM) remain unclear. Imaging studies of the brain could help to identify possible structural brain lesions underlying cognitive dysfunction. OBJECTIVE to describe a detailed neuropsychological profile in patients functioning independently with type 2 DM. Secondly, correlations were studied between cognitive impa...

Cognitive impairment and dementia in Type 2 diabetes

Type 2 diabetes and ethnic disparities in cognitive impairment.

OBJECTIVES We explored whether ethnic differences in type 2 diabetes (T2D) explain ethnic disparities in cognitive impairment. DESIGN Longitudinal study. SETTING A cohort study of multiethnic community-dwelling elderly persons in Northern Manhattan, New York. PARTICIPANTS 941 participants aged > or =65 years without prevalent cognitive impairment or dementia (CID) were followed for a medi...